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The A body shape index and type 2 diabetes are mutually independent predictors of cardiovascular events in patients with peripheral artery disease

Session Poster Session 7

Speaker Christoph Saely

Event : ESC Congress 2018

  • Topic : preventive cardiology
  • Sub-topic : Prevention – Cardiovascular Risk Assessment: Scores
  • Session type : Poster Session

Authors : A Vonbank (Feldkirch,AT), CH Saely (Bern,CH), C Heinzle (Feldkirch,AT), D Zanolin (Feldkirch,AT), B Larcher (Feldkirch,AT), A Mader (Feldkirch,AT), A Leiherer (Triesen,LI), A Muendlein (Feldkirch,AT), H Drexel (Philadelphia,US)

Authors:
A. Vonbank1 , C.H. Saely2 , C. Heinzle3 , D. Zanolin3 , B. Larcher1 , A. Mader1 , A. Leiherer4 , A. Muendlein3 , H. Drexel5 , 1Academic Teaching Hospital, Department of Medicine and Cardiology - Feldkirch - Austria , 2Bern University Hospital, Division of Angiology, Swiss Cardiovascular Center - Bern - Switzerland , 3VIVIT Institute - Feldkirch - Austria , 4Private University of the Principality of Liechtenstein - Triesen - Liechtenstein , 5Drexel University College of Medicine - Philadelphia - United States of America ,

Citation:
European Heart Journal ( 2018 ) 39 ( Supplement ), 1295

Background: The A Body Shape index (ABSI) is calculated based on waist circumference, height and BMI and is a validated measure of visceral adiposity. In the general population, the ABSI has been shown to be an independent risk factor for premature mortality.

Purpose: The purpose of this study was to investigate the power of ABSI to predict cardiovascular events in patients with peripheral artery disease (PAD).

Methods: We prospectively recorded cardiovascular events in 319 patients with sonographically verified PAD over a mean follow-up time of 7.2±2.1 years.

Results: At baseline, the ABSI was significantly higher in patients with type 2 diabetes (T2DM) than in those who did not have diabetes (19.5±1.9 vs. 14.0±1.1; p<0.001). Prospectively, the ABSI significantly predicted the incidence of cardiovascular events (n=57) both univariately (standardized HR 1.36 [1.20–1.52]; p<0.001) and after adjustment for age, gender, smoking, LDL cholesterol, HDL cholesterol, hypertension and T2DM (standardized adjusted HR 1.17 [1.08–1.29]; p=0.010); also T2DM significantly predicted cardiovascular events in this fully adjusted model (adjusted HR 1.48 [1.25–1.74]; p<0.001).

Conclusion: We conclude that the ABSI and T2DM are mutually independent of cardiovascular events in patients with PAD.

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