In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.


This content is currently on FREE ACCESS, enjoy another 101 days of free consultation

 

Educational attainment is an independent predictor of adverse outcomes in patients with coronary artery disease

Session Poster Session 6

Speaker Bahjat Ghazzal

Congress : ESC Congress 2019

  • Topic : coronary artery disease, acute coronary syndromes, acute cardiac care
  • Sub-topic : Coronary Artery Disease - Epidemiology, Prognosis, Outcome
  • Session type : Poster Session
  • FP Number : P5479

Authors : BZ Ghazzal (Atlanta,US), HM Kelli (Atlanta,US), A Mehta (Atlanta,US), AS Tahhan (Atlanta,US), JH Kim (Atlanta,US), TA Dong (Atlanta,US), DS Dhindsa (Atlanta,US), PB Sandesara (Atlanta,US), SS Hayek (Ann Arbor,US), AA Alkhoder (Atlanta,US), C Liu (Atlanta,US), Y Ko (Atlanta,US), V Vaccarino (Atlanta,US), LS Sperling (Atlanta,US), AA Quyyumi (Atlanta,US)

Authors:
BZ Ghazzal1 , HM Kelli2 , A Mehta2 , AS Tahhan2 , JH Kim2 , TA Dong3 , DS Dhindsa3 , PB Sandesara2 , SS Hayek4 , AA Alkhoder1 , C Liu1 , Y Ko1 , V Vaccarino5 , LS Sperling2 , AA Quyyumi2 , 1Emory University, Emory Clinical Cardiovascular Research Institute - Atlanta - United States of America , 2Emory University School of Medicine, Division of Cardiology, Department of Medicine - Atlanta - United States of America , 3Emory University School of Medicine, Department of Medicine - Atlanta - United States of America , 4University of Michigan Medical School, Division of Cardiology, Department of Internal Medicine - Ann Arbor - United States of America , 5Emory University, Rollins School of Public Health - Atlanta - United States of America ,

Citation:

Background:

Educational attainment is an indicator of socioeconomic status and is inversely associated with cardiovascular risk factors and risk for incident coronary artery disease (CAD). Whether the level of educational attainment (EL) in patients with CAD influences outcomes remains understudied.

Purpose:

To ascertain the relationship between EL and adverse outcomes in patients with CAD. We hypothesize that EL will be inversely associated with adverse outcomes in this high-risk patient population.

Methods:

Subjects undergoing cardiac catheterization for known or suspected CAD were recruited in a cardiovascular biobank and had their highest level of educational attainment assessed using predefined options of elementary/middle school, high school, college, or graduate education. The primary outcome of interest was all-cause mortality and secondary outcomes included a composite of cardiovascular deaths and nonfatal myocardial infarction (MI) events, and nonfatal MI events during follow-up. Cox proportional hazards regression models were used to analyze the association between EL and adverse outcomes after adjustment for demographic characteristics, cardiovascular risk factors, cardiovascular medication use, and estimated zip code-based annual family income.

Results: 

Among the 6,318 subjects (mean age 64 years, 63% male, 23% black) enrolled, 998 (16%) had received graduate or a higher qualification, 2,689 (43%) had received a college education, 2,403 (38%) had received a high school education, and 228 (3%) had received elementary/middle school education. During a median follow-up of 3 years,there were 1,110 deaths from all causes, 851 cardiovascular deaths/nonfatal MI, and 286 nonfatal MI events. After adjusting for covariates and compared to patients with graduate education or higher, those with lower EL (elementary/middle school, high school, or college education) had a higher risk of all-cause mortality [hazard ratio 1.66, (95% CI 1.08, 2.54), 1.58 (95% CI 1.22, 2.04), and 1.45 (95% CI 1.13, 1.57), respectively]. Similar findings were observed for secondary outcomes. EL dichotomized at graduate education was associated with all-cause mortality (hazard ratio 1.48, 95% CI 1.16, 1.88), but this relationship was significantly modified by sex (p-interaction 0.023) and the association was attenuated among male patients (hazard ratio 1.23, 95% CI 0.94, 1.61) but not female patients (hazard ratio 2.70, 95% CI 1.53, 4.77).

Conclusions: 

Lower educational attainment is an independent predictor of adverse outcomes in patients with CAD. The causal link between low education level and increased CV risk needs further investigation.

This content is currently on FREE ACCESS, enjoy another 101 days of free consultation

 



Based on your interests

Three reasons why you should become a member

Become a member now
  • 1Access your congress resources all year-round on the New ESC 365
  • 2Get a discount on your next congress registration
  • 3Continue your professional development with free access to educational tools
Become a member now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are