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Usefulness of routine angiographic follow-up in diabetic patients following percutaneous coronary intervention with drug-eluting stents: a nested case-control study within korean population
Authors : YH Kim (Chuncheon City,KR), AY Her (Chuncheon City,KR), SW Rha (Seoul,KP), BG Choi (Seoul,KP), SY Choi (Seoul,KP), JK Byun (Seoul,KP), CU Choi (Seoul,KP), EJ Kim (Seoul,KP), CG Park (Seoul,KP), HS Seo (Seoul,KP), DJ Oh (Seoul,KP)
Background: The usefulness of routine angiographic follow-up (RAF) after percutaneous coronary intervention (PCI) compared with clinical follow-up (CF) in diabetic patients who underwent PCI with drug-eluting stents (DESs) is less well known
Purpose: To compare 3-year clinical outcomes of RAF and CF in diabetic patients
Methods: A total of 843 consecutive diabetic patients who underwent PCI with DESs were enrolled. RAF was performed at 6 to 9 months after the index PCI (n=426). Rest of patients were medically managed and clinically followed (n=417).After propensity score matched (PSM) analysis, 2 propensity-matched groups (262 pairs, n=524, C-statistic = 0.750) were generated. Major adverse cardiac events up to 3 years were compared between the RAF group and the CF group.
Results: During the 3-year follow-up period, the cumulative incidence of target lesion revascularization (TLR, HR, 4.07; 95% CI, 1.18–9.34; p=0.001), target vessel revascularization (TVR, HR, 4.02; 95% CI, 1.93–8.40; p<0.001), non-TVR (HR, 4.92; 95% CI, 1.68–14.4; p=0.004) and MACEs (HR, 2.53; 95% CI, 1.60–4.01, p<0.001) were higher in the RAF group compared with the CF group. (Table and Figure)
Conclusions: RAF following index PCI with DESs in diabetic patients was associated with higher incidence of revascularization and MACEs than CF alone without benefit of mortality or MI reduction.
Cumulative clinical follow-up outcomes between one to three years
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