In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.


The free consultation period for this content is over.

It is now only available year-round to ESC Professional Members, Fellows of the ESC, and Young combined Members

Long- and short-term impacts of hemodialysis on right ventricle: assessment via real-time three-dimensional echocardiography

Session Poster session 2

Speaker Minmin Sun

Congress : ESC Congress 2017

  • Topic : imaging
  • Sub-topic : Echocardiography: Systolic and Diastolic Function
  • Session type : Poster Session
  • FP Number : P1436

Authors : MM Sun (Shanghai,CN), XH Shu (Shanghai,CN), XS Cao (Shanghai,CN), Y Guo (Shanghai,CN), X Tan (Shanghai,CN), LL Dong (Shanghai,CN), CZ Pan (Shanghai,CN), JB Ge (Shanghai,CN)

Authors:
M.M. Sun1 , X.H. Shu1 , X.S. Cao1 , Y. Guo1 , X. Tan1 , L.L. Dong1 , C.Z. Pan1 , J.B. Ge1 , 1Zhongshan Hospital of Fudan University - Shanghai - China People's Republic of ,

Citation:
European Heart Journal ( 2017 ) 38 ( Supplement ), 290

Purpose: Right ventricular (RV) dysfunction is known as a major cause of death in patients with maintenance hemodialysis (MHD). We used conventional and real-time three-dimensional echocardiography (RT-3DE) to evaluate the long-and short-term impact of MHD on RV function.

Methods: Echocardiography was performed on 110 consecutively enrolled individuals, including 30 controls and 80 patients with MHD. Conventional echocardiographic parameters and RT-3DE parameters were obtained. Right ventricular volumes and systolic parameters were analyzed and compared between the two groups to reveal the long-term impact of hemodialysis on RV. Among them, fourteen patients with intradialytic hypotension (IDH) and 14 patients without IDH (non-IDH) were analyzed before and shortly after one hemodialysis session, in order to detect the short-term impact of hemodialysis on RV.

Results: RV end-diastolic volume (EDV-rv) were markedly enlarged (47.1±11.8ml/m2 VS 42.3±8.6 ml/m2, p=0.056), while RV ejection fraction (RVEF) was significantly lower in the MHD patients than the control group (50.6±5.8% VS 55.2±3.7%, p<0.001). The RV global, septal and lateral longitudinal strains (LS-rv, LS-sep, LS-lat) were also decreased in MHD group (LS-rv: -18.2±3.6 VS -22.6±4.3%; LS-sep: -13.1±3.8 VS -17.5±5.5%; LS-lat: -23.4±4.7 VS -27.7±4.0%, all p<0.001). History of coronary heart disease was an independent factor for predicting RVEF reduction. RV diastolic function was impaired in MHD Group, demonstrated by lower tricuspid E/A and E'/A' ratios. For the short-term effects, RVEF and RV longitudinal strains were increased after the HD session in the non-IDH group (RVEF: from 52.0±4.3% to 53.1±4.3%, p=0.067; LS-sep: from -12.7±1.7% to -14.8±2.2%, p=0.001; LS-rv: from -18.2±2.4% to -19.4±1.7%, p=0.033), while RVEF and RV longitudinal strains were decreased in the IDH group (RVEF: from 45.9±2.6% to 43.7±3.4%; LS-sep: from -11.7±2.1% to -10.1±2.1%; LS-lat: from -21.8±4.0% to-18.2±3.8%; LS-rv: from -16.7±2.5% to -14.1±2.1%, all p<0.01). However, RV diastolic function remained unchanged after HD in the two groups.

Conclusions: MHD patients endure the deterioration of right ventricular function. However, one session of HD may have different effects on non-IDH and IDH groups. RT-3DE has potential in the RV evaluation and risk stratification in MHD patients.



Based on your interests

Three reasons why you should become a member

Become a member now
  • 1Access your congress resources all year-round on the New ESC 365
  • 2Get a discount on your next congress registration
  • 3Continue your professional development with free access to educational tools
Become a member now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim and Lilly Alliance, Bristol-Myers Squibb and Pfizer Alliance, Novartis Pharma AG and Vifor Pharma in the form of educational grants. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are