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Comparison of multimodality evaluation of atherosclerosis for assessment of the severity and complexity of coronary artery disease: Flow-mediated dilation, ankle-brachial index and pulse wave velocity

Session Poster session 1

Speaker Yun Young Choi

Event : ESC Congress 2017

  • Topic : coronary artery disease, acute coronary syndromes, acute cardiac care
  • Sub-topic : Coronary Artery Disease (Chronic)
  • Session type : Poster Session

Authors : YY Choi (Seoul,KR), JS Woo (Seoul,KR), JM Kim (Seoul,KR), HO Kim (Seoul,KR), HM Chung (Seoul,KR), JM Lee (Seoul,KR), SJ Kim (Seoul,KR), WS Kim (Seoul,KR), KS Kim (Seoul,KR), W Kim (Seoul,KR), JB Kim (Seoul,KR)

Y.Y. Choi1 , J.S. Woo1 , J.M. Kim1 , H.O. Kim1 , H.M. Chung1 , J.M. Lee1 , S.J. Kim1 , W.S. Kim1 , K.S. Kim1 , W. Kim1 , J.B. Kim1 , 1Kyunghee University, cardiology - Seoul - Korea Republic of ,

European Heart Journal ( 2017 ) 38 ( Supplement ), 194

Background: Flow-mediated dilation (FMD), Ankle-brachial index (ABI) and Pulse wave velocity (PWV) have been used as noninvasive modalities for evaluating atherosclerosis. This study was revealed that which non-invasive atherosclerosis tests could predict complexity and severity of coronary artery disease (CAD).

Methods: From January 2010 to November 2013, 1,630 stable angina patients who performed non-invasive arthrosclerosis evaluation (FMD, ABI, PWV) with diagnostic Coronary angiography (CAG) were enrolled in this study. The primary end point was differences of non-invasive tests according to CAD severity (number of diseased vessel) and complexity (syntax score).

Results: Patients with high syntax score (≥23) showed significantly low values of FMD and ABI and high PWV. CAD extent was significantly associated with ABI (p<0.001). However, there was no significant correlation of CAD extent and FMD (p=0.17), PWV (p=0.06). Non-invasive tests showed incremental predictive values of CAD complexity (Figure).

Conclusion: Different non-invasive tests could be useful to predict CAD severity and complexity in a complementary manner regardless of its purpose in patients with stable angina.

Incremental prediction of CAD complexi

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