In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.


The free consultation period for this content is over.

It is now only available year-round to EHRA Ivory (& above) Members, Fellows of the ESC and Young combined Members

Comparison of risk scores in patients undergoing cardiac resynchronization therapy

Session Poster session 3

Speaker Andras Mihaly Boros

Congress : EHRA 2019

  • Topic : arrhythmias and device therapy
  • Sub-topic : Cardiac Resynchronization Therapy
  • Session type : Poster Session
  • FP Number : P1532

Authors : A M Boros (Budapest,HU), P Perge (Budapest,HU), L Geller (Budapest,HU), B Merkely (Budapest,HU), G Szeplaki (Budapest,HU)

15 views

Authors:
A M Boros1 , P Perge1 , L Geller1 , B Merkely1 , G Szeplaki1 , 1Semmelweis University Heart Center, Cardiology - Budapest - Hungary ,

Citation:

Background
Cardiac resynchronization therapy (CRT) improves the mortality of heart failure, though it remains rather high. Several risk scores have been established to present the long-term benefit of the procedure more realistically.

Purpose
We created the "REDNaILER score" and compared its discriminative power to that of other risk scores including "AL-FINE", "EAARN", "VALID-CRT", "CRT-score", and "Screen".

Methods
We retrospectively analyzed the utility of the above score systems in the prediction of 5-year mortality in 136 consecutive patients undergoing CRT. The "REDNaILER score" is the combination of baseline predictors that have been previously described by our group: REd blood cell Distribution width > 13.35%, NeutrophIl granulocyte to the LymphocytE Ratio > 2.95, lack of left bundle branch block morphology, lack of beta blocker therapy. The presence of any of these variables equals to 1 point. Patients were categorized into low (0-1 points), medium (2 points) and high (3-4) risk groups.

Results
After a median follow-up of 1799 (861-2023) days, 58 patients (42%) died. The discriminative power of the REDNaILER score [c-statistics: 0.74 (0.66-0.82); log-rank p<0.0001] showed comparable performance to AL-FINE [DeLong p=0.17; c-statistics: 0.67 (0.59-0.75); log-rank p<0.0001], EAARN [DeLong p=0.005; c-statistics: 0.59 (0.50-0.67); log-rank p=0.02], VALID-CRT [DeLong p=0.05; c-statistics: 0.65 (0.58-0.72); log-rank p<0.0001], CRT-score [DeLong p=0.16; c-statistics: 0.67 (0.59-0.74); log-rank p<0.0001], and Screen [DeLong p=0.002; c-statistics: 0.57 (0.49-0.66); log-rank p=0.06].

Conclusions
We validated the utility of "AL-FINE", "EAARN", "VALID-CRT", "CRT-score", and "Screen" scores in our CRT patient population and presented the novel "REDNaILER score" that has adequate discriminative power.



Based on your interests

Three reasons why you should become a member

Become a member now
  • 1Access your congress resources all year-round on the New ESC 365
  • 2Get a discount on your next congress registration
  • 3Continue your professional development with free access to educational tools
Become a member now

Our sponsors

ESC 365 is supported by Bayer, Boehringer Ingelheim, Bristol-Myers Squibb and Pfizer Alliance, and Novartis Pharma AG. The sponsors were not involved in the development of this platform and had no influence on its content.

logo esc

Our mission: To reduce the burden of cardiovascular disease

Who we are