Transcatheter mitral valve repair (TMVR) using the Mitraclip® system is an alternative for patients with severe mitral regurgitation (MR) and high surgical risk. Factors affecting survival are under investigation.
Assess the role of right ventricule (RV) systolic function in post-procedure outcomes: survival and heart failure admissions.
Prospective inclusion of patients in whom TMVR was performed between october 2015 and june 2018. RV systolic dysfunction was established as either tricuspid annular plane systolic excursión (TAPSE) less tan 16 mm or systolic tricuspid annular tissue Doppler velocity (TATDV) less tan 9.7 m/s. Chi-square and student´s t-test were use for between group comparisons. Kaplan Meier´s method was used for survival analysis.
44 patients included: 14 with RV systolic dysfunction and 29 with preserved RV systolic function. Basal characteristics are shown in table 1.
Median follow-up was 290 days (interquartile range 90 - 650 days). At one year follow-up, survival rate in patients with RV dysfunction was 74.3% vs 94.12% in patients with preserved RV function (Logrank test = 0.04). Survival free from heart failure admission in the RV systolic dysfunction group was 70.1% vs 78.9% in the group with preserved RV function (Logrank test = 0.3). Mean heart failure admissions during a 12-month period after procedure was 0.8 in the preserved RV function group vs 2.1 in the RV systolic dysfunction one.
RV systolic dysfunction confers a poor prognosis in TMVR patients.