The aim of this study is analyze the impact of significant mitral regurgitation (MR) in patients diagnosed of severe aortic stenosis wihout ischemic heart disease treated with transfemoral TAVI.
Methods and results:
This is a retrospecive study of patiens with severe aortic steneosis (AS) treated with transfemoral TAVI between 2011 and 2018 in tertiary hospital. Significant mitral regurgitation was defined as moderate or severe MR assessed by 2D transthoracic echocardiography.
From the patients that were included in our study, 54.8% (90/164) did not have ischemic heart disease and from this group 23.3% (21/90) had significant MR. The statistically significant differences between patiens with and without significant MR were left ventricular ejection fraction (LVEF) (53.05%vs60.6%;p=0.02), the prevalence of hypertension (92.2%vs71.4%;p=0.02) and mortality (19%vs2.9%;p=0.025) as it is showed in the table 1. When we perfom a survival analysis , it is objectified that patients with significant MR have a lower suvival but without reaching statistical significance (p=0.07) (Figure 1).
The results of our study show that a significant MR clearly affects the mortality of patients with no history of ischemic heart disease who who underwent transfemoral TAVI.