Methods: In the 157 consecutive STEMI patients (pts) in PREDICT-VT study (NCT03263949) treated with pPCI was done early echo (5±2 days) including conventional parameters and comprehensive speckle tracking LV deformation analysis with longitudinal (L), and circumferential (C) strain (S;%) on three layers (endo, mid and epi). ROC analysis was performed to identify the best parameters to predict re-hospitalization.
Results: 11.4% pts re-hospitalized after discharged: 2 due to re-infarction, 5 for heart failure, 4 for unstable angina and 7 for new onset arrhythmia. Re-hospitalized pts were at similar age (59.2±11.1 vs. 56.9±10.1, p=NS), insignificantly more had diabetes (27.8% vs. 24.5%), hypertension (72.2% vs. 67.8%), hyperlipidaemia (50.% vs. 56.6%) and other comorbidities. Peak systolic LS on mid and endo layers were significantly lower, as well as peak systolic CS on each layers in re-hospitalized pts (table). The peak systolic CS on endo layer had the largest area under the ROC (0.697, p=0.011, 95% CI 0.566-0.828) (-18.1%, sens 70.1% and spec 68.6%). Conclusion: Peak systolic LS and peak systolic CS could be used for early stratification of STEMI patients treated by pPCI for re-hospitalization prediction during the first year.