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Effect of cardiac rehabilitation predicts event-free survival

Session Cardiopulmonary exercise and rehabilitation

Speaker Nicolai Mikkelsen

Event : ESC Congress 2019

  • Topic : preventive cardiology
  • Sub-topic : Rehabilitation: Outcomes
  • Session type : Moderated Posters

Authors : N Mikkelsen (Copenhagen,DK), H Rasmusen (Copenhagen,DK), J Reeh (Copenhagen,DK), C Cardarso-Suarez (Santiago de Compostela,ES), O Lado-Baleato (Santiago de Compostela,ES), C Diaz-Louzao (Santiago de Compostela,ES), E Prescott (Copenhagen,DK)

Authors:
N. Mikkelsen1 , H. Rasmusen1 , J. Reeh1 , C. Cardarso-Suarez2 , O. Lado-Baleato2 , C. Diaz-Louzao2 , E. Prescott1 , 1Bispebjerg University Hospital, Department of Cardiology - Copenhagen - Denmark , 2University of Santiago de Compostela, Unit of Biostatistics, Department of Statistics - Santiago de Compostela - Spain ,

Topic(s):
Rehabilitation: Outcomes

Citation:
European Heart Journal ( 2019 ) 40 ( Supplement ), 1877

Background: Participation in cardiac rehabilitation (CR) improves prognosis. Whether more effect of exercise training also affects prognosis is unknown.

Purpose: To investigate whether change in VO2peak after CR is a predictor of future cardiovascular disease and/or mortality

Methods: Retrospective analysis on 1237 cardiac patients completing a CR program in Copenhagen in 2011–2017 with a cardiopulmonary exercise test performed at baseline and end of CR. The association between change in VO2peak and future risk of morbidity and mortality through registry linkage was assessed by Cox regression analysis adjusting for age, sex, cardiac diagnosis, comorbidities and baseline VO2peak.

Results: 1237 patients were included, mean was age 64 (±11) years and 75% were males. 30% of the patients did not improve in VO2peak. There were 166 events and 76 deaths during a median follow-up of 2.3 years. Both baseline VO2peak and change in VO2peak were significantly associated with risk after multivariable adjustment.

Conclusion: Improvement in VO2peak during a CR program is a strong predictor of subsequent prognosis in cardiac patients.

Change in VO2peak: MACE and mortality

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