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High-sensitivity cardiac troponin T and stroke risk in patients admitted to an emergency department with atrial fibrillation

Session Poster session 5

Speaker Kiril M Stoyanov

Event : ESC Congress 2017

  • Topic : arrhythmias and device therapy
  • Sub-topic : Atrial Fibrillation
  • Session type : Poster Session

Authors : M Vafaie (Heidelberg,DE), E Giannitsis (Heidelberg,DE), M Mueller-Hennessen (Heidelberg,DE), M Biener (Heidelberg,DE), E Gorochow (Heidelberg,DE), HA Katus (Heidelberg,DE), KM Stoyanov (Heidelberg,DE)

Authors:
M. Vafaie1 , E. Giannitsis1 , M. Mueller-Hennessen1 , M. Biener1 , E. Gorochow1 , H.A. Katus1 , K.M. Stoyanov1 , 1University Hospital of Heidelberg, Department of Cardiology, Angiology and Pneumology - Heidelberg - Germany ,

Topic(s):
Atrial fibrillation (AF)

Citation:
European Heart Journal ( 2017 ) 38 ( Supplement ), 970-971

Background: Elevated high-sensitivity cardiac troponin T (hsTnT) is known to predict adverse outcomes in patients with atrial fibrillation (AF). Their role in prediction of stroke is still in debate.

Methods: This retrospective study included 2,898 consecutive patients presenting with AF to the emergency department of a Department of Cardiology. Multivariable Cox regression was used to assess associations between hsTnT and stroke.

Results: Elevated hsTnT concentrations were associated with increased risk of stroke in patients with AF. Even after adjustment for multiple risk factors, elevated hsTnT (>14 ng/L) remained an independent predictor of stroke in patients with AF with an adjusted hazard ratio of 2.34 [95% confidence interval: 1.23–4.45] (P=0.009).

Conclusions: Elevated hsTnT levels are significantly associated with higher risk of stroke in patients with AF, even after adjustment for various risk factors. Measurement of hsTnT and its inclusion in scores for stroke risk assessment should be considered in patients presenting to an emergency department with AF.

Kaplan-Meier curve for stroke in AF

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